Anthracycline Drugs

Daunorubicin

Brand/Trade Names: Cerubidine, DaunoXome

Formula: C27H29NO10

Mechanism: Antimetabolite

Class: Antibiotic

Administration: Intraveneous

Notes:  First approved by the FDA in 1979.

Doxorubicin

Brand/Trade Names: Adriamycin, Rubex, Doxil

Formula: C27H29NO11

Mechanism: Antimetabolite

Class: Antibiotic

Administration: Intraveneous

Notes:  Called “the red devil” due to its bright red color and severe side effects.  First approved by the FDA in 1974.

Epirubicin

Brand/Trade Names: Ellence, Pharmorubicin

Formula: C27H29NO11

Mechanism: Antimetabolite

Class: Antibiotic

Administration: Intraveneous

Notes:  Approved by the FDA in 1999.

Idarubicin

Brand/Trade Names: Idamycin

Formula: C26H28ClNO9

Mechanism: Antimetabolite

Class: Antibiotic

Administration: Intraveneous

Notes:  Approved by the FDA in 1990.

Valrubicin



Brand/Trade Names: Valstar

Formula: C34H36F3NO13

Mechanism: Antimetabolite

Class: Antibiotic

Administration: Intravenous

Notes:  Approved by the FDA in 1998.