Antifolates

Pralatrexate

Brand/Trade Names: Folotyn

Formula: C23H23N7O5

Mechanism: Antimetabolite

Class: Antifolate

Administration: Intravenous

Notes:

Pemetrexed

Brand/Trade Names: Alimta

Formula: C20H21N5O6

Mechanism: Antimetabolite

Class: Antifolate

Administration: Intravenous

Notes:

Methotrexate

Brand/Trade Names: MTX, amethopterin

Formula: C20H22N8O5

Mechanism: Antimetabolite

Class: Antifolate

Administration: Intravenous

Notes: Very widely used.

methotrexate molecule

Raltitrexed

Brand/Trade Names: Tomudex

Formula: C21H22N4O6S

Mechanism: Antimetabolite

Class: Antifolate

Administration: Intravenous

Notes: