Mustards

Cyclophosphamide

Brand/Trade Names: Cytoxan, Neosar, Endoxan, Cytophosphane

Formula: C7H15Cl2N2O2P

Mechanism: Alkylating

Class: Mustard

Administration: Intraveneous, oral

Notes: Prodrug that converts to active drug inside the body

Chlorambucil

Brand/Trade Names: Leukeran

Formula: C14H19Cl2NO2

Mechanism: Alkylating

Class: Mustard

Administration: Intraveneous, oral

Notes:

Mechlorethamine

Brand/Trade Names: Mustargen, Mechlorethamine Hydrochloride, mustine, nitrogen mustard, and HN2

Formula: C5H11Cl2N

Mechanism: Alkylating

Class: Mustard

Administration: Intraveneous, topical

Notes:

Bendamustine

Brand/Trade Names: Ribomustin, Treanda, and 4-[5-[Bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid,

Formula: C16H21Cl2N3O2

Mechanism: Alkylating

Class: Mustard

Administration: Intraveneous

Notes:

Estramustine

Brand/Trade Names: Ribomustin, Treanda, and 4-[5-[Bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid,

Formula: C23H31Cl2NO3

Mechanism: Alkylating

Class: Mustard

Administration: Intraveneous and oral

Notes: