Taxanes

These are active in the M-Phase.  In the nucleus of the dividing cell they bind to the microtubules and inhibit their normal function

Paclitaxel

Other generic names:
Forumla:
C47H51NO14
Trade names
Taxol, Abraxane
Class (action)
Class (chemical)
Mitotic Inhibitor Taxanes
Administration
Intravenous
Notes
First discovered as an extract from the bark of the Pacific Yew tree.

Paclitaxel molecule, from National Cancer Institute

 

Docetaxel

Other generic names:
Forumla:
C43H53NO14
Trade names
Taxotere
Class (action)
Class (chemical)
Mitotic Inhibitor Taxanes
Administration
Intravenous
Notes
A semi-synthetic analogue of paclitaxel

Lomustine

Other generic names:
Forumla:
C9H16ClN3O2
Trade names
CeeNU
Class (action)
Class (chemical)
Alkylating Agent Nitrosurea
Administration
Intravenous
Notes
Used for treating brain tumors